Latest Videos - Project Managers 2018-04-25T23:48:02Z http://network.projectmanagers.net/video/video/rss?xn_auth=no proliferation assay tag:network.projectmanagers.net,2018-03-02:1606472:Video:293965 2018-03-02T03:33:19.787Z Candy Swift http://network.projectmanagers.net/profile/CandySwift <a href="http://network.projectmanagers.net/video/proliferation-assay"><br /> <img alt="Thumbnail" height="135" src="http://api.ning.com:80/files/aEnLt2NDQ6WkUAUA*7lSJe6GEMPgg95SyAqZ4ehHjEsDiepAG8ZO4t68LZYyvemi7EdCITOtI6z16u4TPVc*EmQzpQFbAIJz/tmp405299203840046220.png?width=240&amp;height=135" width="240"></img><br /> </a> <br></br>SIAT® DC-T cell proliferation assay uses Flow Cytometry to detect T cell proliferation after co-culture with loaded DCs, which is extremely sensitive and accurate. Specifically, T cells are labeled with 5,6-carboxyfluorescein diacetate succinimidyl ester (CFSE) dye.<br></br> <br></br> Reference:… <a href="http://network.projectmanagers.net/video/proliferation-assay"><br /> <img src="http://api.ning.com:80/files/aEnLt2NDQ6WkUAUA*7lSJe6GEMPgg95SyAqZ4ehHjEsDiepAG8ZO4t68LZYyvemi7EdCITOtI6z16u4TPVc*EmQzpQFbAIJz/tmp405299203840046220.png?width=240&amp;height=135" width="240" height="135" alt="Thumbnail" /><br /> </a><br />SIAT® DC-T cell proliferation assay uses Flow Cytometry to detect T cell proliferation after co-culture with loaded DCs, which is extremely sensitive and accurate. Specifically, T cells are labeled with 5,6-carboxyfluorescein diacetate succinimidyl ester (CFSE) dye.<br /> <br /> Reference: <a href="https://www.creative-biolabs.com/SIAT-DC-T-cell-proliferation-assay.html">https://www.creative-biolabs.com/SIAT-DC-T-cell-proliferation-assay.html</a> Keytruda tag:network.projectmanagers.net,2018-03-02:1606472:Video:293702 2018-03-02T03:31:23.932Z Candy Swift http://network.projectmanagers.net/profile/CandySwift <a href="http://network.projectmanagers.net/video/keytruda"><br /> <img alt="Thumbnail" height="135" src="http://api.ning.com:80/files/aEnLt2NDQ6W137WuwweclGmJy0THm9hxYRP1t29KefzBIIQSJFR5lPjJqZqga9H7pYHgVHRa-RYANStd-ucObbLXVBo0iS-J/tmp2836596884651537882.png?width=240&amp;height=135" width="240"></img><br /> </a> <br></br>Recombinant Humanized (from mouse) antibody to Human PDCD1. It is a drug that targets the programmed cell death 1 (PD-1) receptor. The drug is intended for use in treating metastatic melanoma.…<br></br> <br></br> <a href="http://network.projectmanagers.net/video/keytruda"><br /> <img src="http://api.ning.com:80/files/aEnLt2NDQ6W137WuwweclGmJy0THm9hxYRP1t29KefzBIIQSJFR5lPjJqZqga9H7pYHgVHRa-RYANStd-ucObbLXVBo0iS-J/tmp2836596884651537882.png?width=240&amp;height=135" width="240" height="135" alt="Thumbnail" /><br /> </a><br />Recombinant Humanized (from mouse) antibody to Human PDCD1. It is a drug that targets the programmed cell death 1 (PD-1) receptor. The drug is intended for use in treating metastatic melanoma.<br /> <br /> <a href="https://www.creativebiolabs.net/Anti-Human-PDCD1-Therapeutic-Antibody-13678.htm">https://www.creativebiolabs.net/Anti-Human-PDCD1-Therapeutic-Antibody-13678.htm</a> humanized monkey antibody tag:network.projectmanagers.net,2018-03-02:1606472:Video:293963 2018-03-02T03:17:54.903Z Candy Swift http://network.projectmanagers.net/profile/CandySwift <a href="http://network.projectmanagers.net/video/humanized-monkey-antibody"><br /> <img alt="Thumbnail" height="135" src="http://api.ning.com:80/files/aEnLt2NDQ6WEMESLcAYZsogiBHAr9AT-CNDXu2Zh97tMXpvwTtpN*qvPYMmBEBA5-K-H2Shkiswknco5ICvUS36rPX2bEF4v/tmp6712958956786824303.png?width=240&amp;height=135" width="240"></img><br /> </a> <br></br>On the Universal Antibody Humanization platform, three-dimensional modeling of two vital monkey antibody frameworks is employed to identify the mutations that do not alter the parental antibody structure. After that, monkey antibodies are germline-humanized to frameworks very similar to human IgMs, which is supposed to be the best tolerated frameworks for therapeutic use while… <a href="http://network.projectmanagers.net/video/humanized-monkey-antibody"><br /> <img src="http://api.ning.com:80/files/aEnLt2NDQ6WEMESLcAYZsogiBHAr9AT-CNDXu2Zh97tMXpvwTtpN*qvPYMmBEBA5-K-H2Shkiswknco5ICvUS36rPX2bEF4v/tmp6712958956786824303.png?width=240&amp;height=135" width="240" height="135" alt="Thumbnail" /><br /> </a><br />On the Universal Antibody Humanization platform, three-dimensional modeling of two vital monkey antibody frameworks is employed to identify the mutations that do not alter the parental antibody structure. After that, monkey antibodies are germline-humanized to frameworks very similar to human IgMs, which is supposed to be the best tolerated frameworks for therapeutic use while retaining the parental affinity.<br /> <br /> Reference: <a href="https://www.creative-biolabs.com/Humanization-of-Monkey-NHP-Antibodies.html">https://www.creative-biolabs.com/Humanization-of-Monkey-NHP-Antibodies.html</a> Human Synovium Targeting tag:network.projectmanagers.net,2018-03-02:1606472:Video:293695 2018-03-02T03:16:39.870Z Candy Swift http://network.projectmanagers.net/profile/CandySwift <a href="http://network.projectmanagers.net/video/human-synovium-targeting"><br /> <img alt="Thumbnail" height="135" src="http://api.ning.com:80/files/aEnLt2NDQ6UyAGigmOgWh5-kXEeAits483NmEsIxHlMEz*CtN**hNCn0YxbUlzntTFAlmwTDtyJ-JFJ0FCHr3PChqABMTkLu/tmp5107562078843443509.png?width=240&amp;height=135" width="240"></img><br /> </a> <br></br>Synovium, also known as synovial membrane or stratum synovial, is soft tissue found between the joint capsule and the joint cavity of synovial joints. One common disease relates to synovium is the rheumatoid arthritis (RA). RA can be recognized by the proliferative synovitis which is involved in cartilage and bone damage and then resulting in progressive joint destruction.… <a href="http://network.projectmanagers.net/video/human-synovium-targeting"><br /> <img src="http://api.ning.com:80/files/aEnLt2NDQ6UyAGigmOgWh5-kXEeAits483NmEsIxHlMEz*CtN**hNCn0YxbUlzntTFAlmwTDtyJ-JFJ0FCHr3PChqABMTkLu/tmp5107562078843443509.png?width=240&amp;height=135" width="240" height="135" alt="Thumbnail" /><br /> </a><br />Synovium, also known as synovial membrane or stratum synovial, is soft tissue found between the joint capsule and the joint cavity of synovial joints. One common disease relates to synovium is the rheumatoid arthritis (RA). RA can be recognized by the proliferative synovitis which is involved in cartilage and bone damage and then resulting in progressive joint destruction.<br /> <br /> Resource: <a href="https://www.creative-biolabs.com/In-vivo-Phage-Display-for-Human-Synovium-Targeting.htm">https://www.creative-biolabs.com/In-vivo-Phage-Display-for-Human-Synovium-Targeting.htm</a> fab construction tag:network.projectmanagers.net,2018-03-02:1606472:Video:293786 2018-03-02T03:14:40.305Z Candy Swift http://network.projectmanagers.net/profile/CandySwift <a href="http://network.projectmanagers.net/video/fab-construction"><br /> <img alt="Thumbnail" height="135" src="http://api.ning.com:80/files/aEnLt2NDQ6VG4GmIWrRZwy*XKWUiiNnlGRODHIDCmhkV5cB7W-5w-QaSjhdAGtACIjxyvV2BVRg8P7P4uG6IwzdTyNo0QFPy/tmp4891593499060744301.png?width=240&amp;height=135" width="240"></img><br /> </a> <br></br>Creative Biolabs has established a solid platform for scFv and Fab construction. There are three routes to have a scFv or Fab targets a specific antigen.<br></br> <br></br> Resource:… <a href="http://network.projectmanagers.net/video/fab-construction"><br /> <img src="http://api.ning.com:80/files/aEnLt2NDQ6VG4GmIWrRZwy*XKWUiiNnlGRODHIDCmhkV5cB7W-5w-QaSjhdAGtACIjxyvV2BVRg8P7P4uG6IwzdTyNo0QFPy/tmp4891593499060744301.png?width=240&amp;height=135" width="240" height="135" alt="Thumbnail" /><br /> </a><br />Creative Biolabs has established a solid platform for scFv and Fab construction. There are three routes to have a scFv or Fab targets a specific antigen.<br /> <br /> Resource: <a href="https://www.creative-biolabs.com/scfv-fab-generation.html">https://www.creative-biolabs.com/scfv-fab-generation.html</a>